Ing. Lucie Petrásková, Ph.D.

Vědecký pracovník

Publikace

Expanding Rutinosidase Versatility: Acylated Quercetin Glucopyranosides as Substrates

Three-Step Enzymatic Remodeling of Chitin into Bioactive Chitooligomers

Galectin-targeting glycocalix[4]arenes can enter the cells

Glycocalix[4]arenes and their affinity to a library of galectins: the linker matters

Sulfation of Phenolic Acids: Chemoenzymatic vs. Chemical Synthesis

New Bacterial Aryl Sulfotransferases: Effective Tools for Sulfation of Polyphenols

Mutation Hotspot for Changing the Substrate Specificity of beta-N-Acetylhexosaminidase: A Library of GlcNAcases

Bacterial Aryl Sulfotransferases in Selective and Sustainable Sulfation of Biologically Active Compounds using Novel Sulfate Donors

Hypertransglycosylating Variants of the GH20 beta-N-Acetylhexosaminidase for the Synthesis of Chitooligomers

Sulfated Phenolic Substances: Preparation and Optimized HPLC Analysis

Engineered Glycosidases for the Synthesis of Analogs of Human Milk Oligosaccharides

Glycopolymers Decorated with 3-O-Substituted Thiodigalactosides as Potent Multivalent Inhibitors of Galectin-3

Mutagenesis of Catalytic Nucleophile of beta-Galactosidase Retains Residual Hydrolytic Activity and Affords a Transgalactosidase

Immunoprotective neo-glycoproteins: Chemoenzymatic synthesis of multivalent glycomimetics for inhibition of cancer-related galectin-3

Data sharing in PredRet for accurate prediction of retention time: Application to plant food bioactive compounds

Sulfated Metabolites of Luteolin; Myricetin; and Ampelopsin: Chemoenzymatic Preparation and Biophysical Properties

Biocatalyzed Reactions towards Functional Food Components 4-Alkylcatechols and Their Analogues

Transglycosidase activity of glycosynthase-type mutants of a fungal GH20 beta-N-acetylhexosaminidase

How Site-Directed Mutagenesis Boosted Selectivity of a Promiscuous Enzyme

Plant Nitrilase Homologues in Fungi: Phylogenetic and Functional Analysis with Focus on Nitrilases in Trametes versicolor and Agaricus bisporus

Multidrug Resistance Modulation Activity of Silybin Derivatives and Their Anti-Inflammatory Potential

Regioselective 3-O-Substitution of Unprotected Thiodigalactosides: Direct Route to Galectin Inhibitors

Mitochondrial Superoxide Production Decreases on Glucose-Stimulated Insulin Secretion in Pancreatic beta Cells Due to Decreasing Mitochondrial Matrix NADH/NAD(+) Ratio

Simple and Rapid HPLC Separation and Quantification of Flavonoid; Flavonolignans; and 2;3-Dehydroflavonolignans in Silymarin

A novel enzymatic tool for transferring GalNAc moiety onto challenging acceptors

Biotransformation of Silymarin Flavonolignans by Human Fecal Microbiota

Acceptor Specificity of ?-N-Acetylhexosaminidase from Talaromyces flavus: A Rational Explanation

Genetic and Functional Diversity of Nitrilases in Agaricomycotina

The effect of silymarin flavonolignans and their sulfated conjugates on platelet aggregation and blood vessels ex vivo

Heterogenní způsob výroby rutinosy

Chemoenzymatic Synthesis and Radical Scavenging of Sulfated Hydroxytyrosol; Tyrosol; and Acetylated Derivatives

Preparation of Retinoyl-Flavonolignan Hybrids and Their Antioxidant Properties

Potential of Mitochondria-Targeted Antioxidants to Prevent Oxidative Stress in Pancreatic beta-cells

Glycosidase-Catalyzed Synthesis of Glycosyl Esters and Phenolic Glycosides of Aromatic Acids

Oxidation of flavonolignan silydianin to unexpected lactone-acid derivative

Isolated Silymarin Flavonoids Increase Systemic and Hepatic Bilirubin Concentrations and Lower Lipoperoxidation in Mice

Bioproduction of Quercetin and Rutinose Catalyzed by Rutinosidase: Novel Concept of´Solid State Biocatalysis´