Differential effects of 40S ribosome recycling factors on reinitiation at regulatory uORFs in GCN4 mRNA are not dictated by their roles in bulk 40S recycling 2024 Laboratoř regulace genové expreseJendruchová K.Gaikwad S.Poncová K.Gunišová S.Valášek L.Hinnebusch A.Communications Biology. 2024; 7(September 2024); 108310.1038/s42003-024-06761-x
Stem-loop-induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control. 2024 Laboratoř regulace genové expreseSmirnova A.Hronová V.Mohammad M.Herrmannová A.Gunišová S.Petráčková D.Halada P.Coufal .Swirski M.Rendleman J.Jendruchová K.Hatzoglou M.Beznosková P.Vogel C.Valášek L.Cell Reports. 2024; 43(4); 11397610.1016/j.celrep.2024.113976
RIP-seq reveals RNAs that interact with RNA polymerase and primary sigma factors in bacteria 2024 Laboratoř mikrobiální genetiky a genové exprese Vaňková Hausnerová V.Shoman M.Kumar D.Schwarz M.Modrák M.Jirát Matějčková J.Mikesková E.Neva S.Herrmannová A.Šiková M.Halada P.Novotná I.Pajer J.Valášek L.Převorovský M.Krásný L.Hnilicová J.Nucleic Acids Research. 2024; 52(May 8); 4604-462610.1093/nar/gkae081
Cysteine tRNA acts as a stop codon readthrough-inducing tRNA in the human HEK293T cell line 2023 Laboratoř regulace genové expreseValášek L.Kučerová M.Zeman J.Beznosková P.RNA. 2023; 29(9); 1379-138710.1261/rna.079688.123
Short tRNA anticodon stem and mutant eRF1 allow stop codon reassignment 2023 Laboratoř regulace genové expreseKachale A.Pavlíková Z.Nenarokova A.Roithová A.Durante I.Miletínová P.Záhonová K.Nenarokov S.Votýpka J.Horáková E.Ross R.Yurchenko V.Beznosková P.Paris Z.Valášek L.Lukeš J.Nature. 2023; 613(7965); 751-75810.1038/s41586-023-06260-9
ZOMES: Cell physiology determined by PCI complexes and protein turnover 2023 Laboratoř regulace genové expreseDubiel D.da Fonseca P.Valášek L.Schulze-Niemand E.Naumann M.Biochimica Et Biophysica Acta-Molecular Cell Research. 2023; 1870(2); 11940210.1016/j.bbamcr.2022.119402
Human DUS1L catalyzes dihydrouridine modification at tRNA positions 16/17; and iDUS1L/i overexpression perturbs translation 2024 Laboratoř regulace genové expreseMatsuura J.Akichika S.Wei F.Suzuki T.Yamamoto T.Watanabe Y.Valášek L.Mukasa A.Tomizawa K.Chujo T.Communications Biology. 2024; 7(1); 123810.1038/s42003-024-06942-8
Selective footprinting of 40S and 80S ribosome subpopulations (Sel-TCP-seq) to study translation and its control 2022 Laboratoř regulace genové expreseWagner S.Bohlen J.Herrmannová A.Jelínek J.Preiss T.Valášek L.Teleman A.Nature Protocols. 2022; 17(10); 2139-218710.1038/s41596-022-00708-4
eIF4G is retained on ribosomes elongating and terminating on short upstream ORFs to control reinitiation in yeast 2021 Laboratoř regulace genové expreseMohammad M.Smirnova A.Gunišová S.Valášek L.Nucleic Acids Research. 2021; 49(15); 8743-875610.1093/nar/gkab652
Increased expression of tryptophan and tyrosine tRNAs elevates stop codon readthrough of reporter systems in human cell lines 2021 Laboratoř regulace genové expreseBeznosková P.Bidou L.Namy O.Valášek L.Nucleic Acids Research. 2021; 49(9); 5202-521510.1093/nar/gkab315
Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts 2020 Laboratoř regulace genové expreseBochler A.Querido J.Prilepskaja T.Soufari H.Simonetti A.Del Cistia M.Kuhn L.Ribeiro A.Valášek L.Hashem Y.Cell Reports. 2020; 33(12); 10853410.1016/j.celrep.2020.108534
Selective Translation Complex Profiling Reveals Staged Initiation and Co-translational Assembly of Initiation Factor Complexes 2020 Laboratoř regulace genové expreseWagner S.Herrmannová A.Hronová V.Gunišová S.Sen N.Hannan R.Hinnebusch A.Shirokikh N.Preiss T.Valášek L.Molecular Cell. 2020; 79(4); 546-56010.1016/j.molcel.2020.06.004
Adapted formaldehyde gradient cross-linking protocol implicates human eIF3d and eIF3c; k and I subunits in the 43S and 48S pre-initiation complex assembly; respectively 2020 Laboratoř regulace genové expreseHerrmannová A.Prilepskaja T.Wagner S.Šikrová D.Zeman J.Poncová K.Valášek L.Nucleic Acids Research. 2020; 48(4); 1969-198410.1093/nar/gkz1185
uS3/Rps3 controls fidelity of translation termination and programmed stop codon readthrough in co-operation with eIF3 2019 Laboratoř regulace genové expresePoncová K.Wagner S.Jansen M.Beznosková P.Gunišová S.Herrmannová A.Zeman J.Dong J.Valášek L.Nucleic Acids Research. 2019; 47(21); 11326-1134310.1093/nar/gkz929
Yeast applied readthrough inducing system (YARIS): an invivo assay for the comprehensive study of translational readthrough 2019 Laboratoř regulace genové expreseBeznosková P.Pavlíková Z.Zeman J.Aitken C.Valášek L.Nucleic Acids Research. 2019; 47(12); 6339-635010.1093/nar/gkz346
Binding of eIF3 in complex with eIF5 and eIF1 to the 40S ribosomal subunit is accompanied by dramatic structural changes 2019 Laboratoř strukturní biologie a buněčné signalizace Zeman J.Itoh Y.Kukačka Z.Rosůlek M.Kavan D.Kouba T.Jansen M.Mohammad M.Novák P.Valášek L.Nucleic Acids Research. 2019; 47(15); 8282-830010.1093/nar/gkz570
