Communications Biology. 2024; 7(September 2024); 1083
Dr. rer. nat. Leoš Valášek, DSc.
Head of Laboratory
Publication
Cell Reports. 2024; 43(4); 113976
Stem-loop-induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control.
Nucleic Acids Research. 2024; 52(May 8); 4604-4626
RIP-seq reveals RNAs that interact with RNA polymerase and primary sigma factors in bacteria
Communications Biology. 2024; 7(1); 1238
Human DUS1L catalyzes dihydrouridine modification at tRNA positions 16/17; and iDUS1L/i overexpression perturbs translation
RNA. 2023; 29(9); 1379-1387
Cysteine tRNA acts as a stop codon readthrough-inducing tRNA in the human HEK293T cell line
Nature. 2023; 613(7965); 751-758
Short tRNA anticodon stem and mutant eRF1 allow stop codon reassignment
Biochimica Et Biophysica Acta-Molecular Cell Research. 2023; 1870(2); 119402
ZOMES: Cell physiology determined by PCI complexes and protein turnover
Nature Protocols. 2022; 17(10); 2139-2187
Selective footprinting of 40S and 80S ribosome subpopulations (Sel-TCP-seq) to study translation and its control
Nucleic Acids Research. 2021; 49(15); 8743-8756
eIF4G is retained on ribosomes elongating and terminating on short upstream ORFs to control reinitiation in yeast
Nucleic Acids Research. 2021; 49(9); 5202-5215
Increased expression of tryptophan and tyrosine tRNAs elevates stop codon readthrough of reporter systems in human cell lines
Cell Reports. 2020; 33(12); 108534
Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts
Molecular Cell. 2020; 79(4); 546-560
Selective Translation Complex Profiling Reveals Staged Initiation and Co-translational Assembly of Initiation Factor Complexes
Nucleic Acids Research. 2020; 48(4); 1969-1984
Adapted formaldehyde gradient cross-linking protocol implicates human eIF3d and eIF3c; k and I subunits in the 43S and 48S pre-initiation complex assembly; respectively
Nucleic Acids Research. 2019; 47(21); 11326-11343
uS3/Rps3 controls fidelity of translation termination and programmed stop codon readthrough in co-operation with eIF3
Nucleic Acids Research. 2019; 47(12); 6339-6350
Yeast applied readthrough inducing system (YARIS): an invivo assay for the comprehensive study of translational readthrough
Nucleic Acids Research. 2019; 47(15); 8282-8300