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Highly functionalized diaminocyclopentanes: A new route to potent and selective inhibitors of human O-GlcNAcase 2023 Laboratoř biotransformacíWeber P.Mészáros Z.Bojarová P.Ebner M.Fischer R.Křen V.Kulik N.Müller P.Vlachová M.Slámová K.Stütz A.Thonhofer M.Torvisco A.Wrodnigg T.Wolfsgruber A.Bioorganic Chemistry. 2023; 140(November 2023); 10681910.1016/j.bioorg.2023.106819
Oligosaccharide Ligands of Galectin-4 and Its Subunits: Multivalency Scores Highly 2023 Laboratoř biotransformacíSlámová K.Červený J.Mészáros Z.Friede T.Vrbata D.Křen V.Bojarová P.Molecules. 2023; 28(10); 403910.3390/molecules28104039
Mutation Hotspot for Changing the Substrate Specificity of beta-N-Acetylhexosaminidase: A Library of GlcNAcases 2022 Laboratoř biotransformacíNekvasilová P.Kulik N.Kotík M.Petrásková L.Slámová K.Křen V.Bojarová P.International Journal of Molecular Sciences. 2022; 23(20); 1245610.3390/ijms232012456
Bacterial Aryl Sulfotransferases in Selective and Sustainable Sulfation of Biologically Active Compounds using Novel Sulfate Donors 2022 Laboratoř biotransformacíBrodsky K.Káňová K.Konvalinková D.Slámová K.Pelantová H.Valentová K.Bojarová P.Křen V.Petrásková L.ChemSusChem. 2022; 15(18); e20220125310.1002/cssc.202201253
Diaminocyclopentane-derived O-GlcNAcase inhibitors for combating tau hyperphosphorylation in Alzheimer’s disease 2022 Laboratoř biotransformacíWeber P.Mészáros Z.Jagecic D.Hribljan V.Mitrečic D.Bojarová P.Slámová K.Vrba J.Kulik N.Křen V.Stuetz A.Chemical Communications. 2022; 58(63); 8838-884110.1039/d2cc02712g
Discovery of human hexosaminidase inhibitors by in situ screening of a library of mono- and divalent pyrrolidine iminosugars 2022 Laboratoř biotransformacíPingitore V.Martinez-Bailen M.Carmona A.Mészáros Z.Kulik N.Slámová K.Křen V.Bojarová P.Robina I.Moreno-Vargas A.Bioorganic Chemistry. 2022; 120(March 2022); 10565010.1016/j.bioorg.2022.105650
Hypertransglycosylating Variants of the GH20 beta-N-Acetylhexosaminidase for the Synthesis of Chitooligomers 2022 Laboratoř biotransformacíMészáros Z.Petrásková L.Kulik N.Pelantová H.Bojarová P.Křen V.Slámová K.Advanced Synthesis & Catalysis. 2022; 364(12); 2009-202210.1002/adsc.202200046
Engineered Glycosidases for the Synthesis of Analogs of Human Milk Oligosaccharides 2022 Laboratoř biotransformacíNekvasilová P.Hovorková M.Mészáros Z.Petrásková L.Pelantová H.Křen V.Slámová K.Bojarová P.International Journal of Molecular Sciences. 2022; 23(8); 410610.3390/ijms23084106
2-Acetamido-2-deoxy-d-glucono-1;5-lactone Sulfonylhydrazones: Synthesis and Evaluation as Inhibitors of Human OGA and HexB Enzymes 2022 Laboratoř biotransformacíKiss M.Timari I.Barna T.Mészáros Z.Slámová K.Bojarová P.Křen V.Hayes J.Somsák L.International Journal of Molecular Sciences. 2022; 23(3); 103710.3390/ijms23031037
Advanced glycosidases as ingenious biosynthetic instruments 2021 Laboratoř biotransformacíMészáros Z.Nekvasilová P.Bojarová P.Křen V.Slámová K.Biotechnology Advances. 2021; 49(JUL-AUG); 10773310.1016/j.biotechadv.2021.107733
Interaction between Galectin-3 and Integrins Mediates Cell-Matrix Adhesion in Endothelial Cells and Mesenchymal Stem Cells 2021 Laboratoř biotransformacíSedlář A.Trávníčková M.Bojarová P.Vlachová M.Slámová K.Křen V.Bačáková L.International Journal of Molecular Sciences. 2021; 22(10); 514410.3390/ijms22105144
Growth Factors VEGF-A(165) and FGF-2 as Multifunctional Biomolecules Governing Cell Adhesion and Proliferation 2021 Laboratoř biotransformacíSedlář A.Trávníčková M.Matějka R.Pražák Š.Mészáros Z.Bojarová P.Bačáková L.Křen V.Slámová K.International Journal of Molecular Sciences. 2021; 22(4); 184310.3390/ijms22041843
Transglycosidase activity of glycosynthase-type mutants of a fungal GH20 beta-N-acetylhexosaminidase 2020 Laboratoř biotransformacíKapešová J.Petrásková L.Kulik N.Straková Z.Bojarová P.Markošová K.Rebroš M.Křen V.Slámová K.International Journal of Biological Macromolecules. 2020; 161(OCT15); 1206-121510.1016/j.ijbiomac.2020.05.273
How Site-Directed Mutagenesis Boosted Selectivity of a Promiscuous Enzyme 2020 Laboratoř biotransformacíNekvasilová P.Kulik N.Rychlá N.Pelantová H.Petrásková L.Bosáková Z.Cvačka J.Slámová K.Křen V.Bojarová P.Advanced Synthesis & Catalysis. 2020; 362(19); 4138-415010.1002/adsc.202000604
Dead Rhizophagus irregularis biomass mysteriously stimulates plant growth 2020 Laboratoř biologie hubJansa J.Šmilauer P.Borovička J.Hršelová H.Forczek S.Slámová K.Řezanka T.Rozmoš M.Bukovská P.Gryndler M.Mycorrhiza. 2020; 30(1); 63-7710.1007/s00572-020-00937-z
Selective Beta-N-acetylhexosaminidase from Aspergillus versicolor—a tool for producing bioactive carbohydrates 2019 Laboratoř biotransformacíBojarová P.Kulik N.Slámová K.Hubálek M.Kotík M.Cvačka J.Pelantová H.Křen V.Applied Microbiology and Biotechnology. 2019; 103(4); 1737-175310.1007/s00253-018-9534-z
The beta-N-Acetylhexosaminidase in the Synthesis of Bioactive Glycans: Protein and Reaction Engineering 2019 Laboratoř biotransformacíBojarová P.Kulik N.Hovorková M.Slámová K.Pelantová H.Křen V.Molecules. 2019; 24(3); 59910.3390/molecules24030599