Microbiological Research. 2025; 292(March 2025); 128043
Mgr. Ladislav Bumba, Ph.D.
Vědecký pracovník
Publikace
Journal of Biological Chemistry. 2025; 301(7); 110392
Acyl chains stabilize the acylated domain and determine the receptor-mediated interaction of the Bordetella adenylate cyclase toxin with cell membrane
Journal of Biological Chemistry. 2023; 299(9); 105150
The adenylate cyclase toxin RTX domain follows a series templated folding mechanism with implications for toxin activity
Microbiology Spectrum. 2023; 11(3); 0411222
BopN is a Gatekeeper of the Bordetella Type III Secretion System
Bioorganic Chemistry. 2023; 131(February); 106279
Advanced high-affinity glycoconjugate ligands of galectins
Journal of Biological Chemistry. 2023; 299(8); 104978
A conserved tryptophan in the acylated segment of RTX toxins controls their ?inf2/inf integrin–independent cell penetration
PLoS Pathogens. 2022; 18(6); e1010577
Pertussis toxin suppresses dendritic cell-mediated delivery of B. pertussis into lung-draining lymph nodes
Nature Communications. 2022; 13(1); 5502
The AAA plus ATPase RavA and its binding partner ViaA modulate E. coli aminoglycoside sensitivity through interaction with the inner membrane
Journal of Medicinal Chemistry. 2022; 65(5); 3866-3878
Glycopolymers Decorated with 3-O-Substituted Thiodigalactosides as Potent Multivalent Inhibitors of Galectin-3
Scientific Reports. 2021; 11(1); 19814
Different roles of conserved tyrosine residues of the acylated domains in folding and activity of RTX toxins
Journal of Biological Chemistry. 2021; 296(JAN-JUN 2021); 100607
Lipid binding by the N-terminal motif mediates plasma membrane localization of Bordetella effector protein BteA
Journal of Biological Chemistry. 2021; 297(1); 100833
Almost half of the RTX domain is dispensable for complement receptor 3 binding and cell-invasive activity of the Bordetella adenylate cyclase toxin
European Journal of Medicinal Chemistry. 2021; 220(AUG 5 2021); 113500
Immunoprotective neo-glycoproteins: Chemoenzymatic synthesis of multivalent glycomimetics for inhibition of cancer-related galectin-3
Vaccines. 2020; 8(4); 695
Acellular Pertussis Vaccine Inhibits Bordetella pertussis Clearance from the Nasal Mucosa of Mice
Toxins. 2020; 12(9); 596
Production of Highly Active Recombinant Dermonecrotic Toxin ofBordetella Pertussis
Journal of Molecular Biology. 2020; 432(20); 5696-5710
Continuous Assembly of beta-Roll Structures Is Implicated in the Type I-Dependent Secretion of Large Repeat-in-Toxins (RTX) Proteins
Chemistry - A European Journal. 2020; 26(43); 9620-9631
Regioselective 3-O-Substitution of Unprotected Thiodigalactosides: Direct Route to Galectin Inhibitors
Biomacromolecules. 2020; 21(8); 3122-3133
Glycopolymers for efficient inhibition of galectin-3: in vitro proof of efficacy using suppression of T lymphocyte apoptosis and tumor cell migration
Biochimica Et Biophysica Acta-Biomembranes. 2020; 1862(9); 183310
Negative charge of the AC-to-Hly linking segment modulates calcium-dependent membrane activities of Bordetella adenylate cyclase toxin
mBio. 2020; 11(2); e00226-20