Data-Independent Acquisition Represents a Promising Alternative for Fast Photochemical Oxidation of Proteins (FPOP) Samples Analysis 2024 Laboratoř strukturní biologie a buněčné signalizace Zákopčaník M.Kavan D.Kukačka Z.Novák P.Loginov D.Analytical Chemistry. 2024; 96(28); 11273-1127910.1021/acs.analchem.4c01084
Top-Down Proteoform Analysis by 2D MS with Quadrupolar Detection 2023 Laboratoř strukturní biologie a buněčné signalizace Polák M.Palasser M.Kádek A.Kavan D.Wootton C.Delsuc M.Breuker K.Novák P.van Agthoven M.Analytical Chemistry. 2023; 95(44); 16123-1613010.1021/acs.analchem.3c02225
Restored biosynthetic pathways induced by MSCs serve as rescue mechanism in leukemia cells after L-asparaginase therapy 2023 Laboratoř strukturní biologie a buněčné signalizace Alquezar-Artieda N.Kužílková D.Roberts J.Hložková K.Pecinová A.Pecina P.Zwyrtková M.Potůčková E.Kavan D.Heřmanová I.Žaliová M.Novák P.Mráček T.Šrámková L.Tennant D.Trka J.Starková J.Blood Advances. 2023; 7(10); 2228-223610.1182/bloodadvances.2021006431
Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease-associated NQO1 enzyme 2023 Laboratoř strukturní biologie a buněčné signalizace Pacheco-Garcia J.Anoz-Carbonell E.Loginov D.Kavan D.Salido E.Man P.Medina M.Pey A.FEBS Journal. 2023; 290(7); 1855-187310.1111/febs.16677
A single evolutionarily divergent mutation determines the different FAD-binding affinities of human and rat NQO1 due to site-specific phosphorylation 2022 Laboratoř strukturní biologie a buněčné signalizace Luis Pacheco-Garcia J.Loginov D.Rizzuti B.Vaňková P.Neira J.Kavan D.Mesa-Torres N.Guzzi R.Man P.Pey A.FEBS Letters. 2022; 596(1); 29-4110.1002/1873-3468.14238
Top-Down Detection of Oxidative Protein Footprinting by Collision-Induced Dissociation;Electron-Transfer Dissociation; and Electron-Capture Dissociation 2022 Laboratoř strukturní biologie a buněčné signalizace Yassaghi G.Kukačka Z.Fiala J.Kavan D.Halada P.Volný M.Novák P.Analytical Chemistry. 2022; 94(28); 9993-1000210.1021/acs.analchem.1c05476
Structural basis for long-chain isoprenoid synthesis by cis-prenyltransferases 2022 Laboratoř strukturní biologie a buněčné signalizace Giladi M.Bar-El M.Vaňková P.Ferofontov A.Melvin E.Alkaderi S.Kavan D.Redko B.Haimov E.Wiener R.Man P.Haitin Y.Science Advances. 2022; 8(20); eabn117110.1126/sciadv.abn1171
Utilization of Fast Photochemical Oxidation of Proteins and Both Bottom-up and Top-down Mass Spectrometry for Structural Characterization of a Transcription Factor-dsDNA Complex 2022 Laboratoř strukturní biologie a buněčné signalizace Polák M.Yassaghi G.Kavan D.Filandr F.Fiala J.Kukačka Z.Halada P.Loginov D.Novák P.Analytical Chemistry. 2022; 94(7); 3203-321010.1021/acs.analchem.1c04746
LinX 2.0 2021 Laboratoř strukturní biologie a buněčné signalizace Kukačka Z.Rosůlek M.Jelínek J.Slavata L.Kavan D.Novák P.
LinX: A Software Tool for Uncommon Cross-Linking Chemistry 2021 Laboratoř strukturní biologie a buněčné signalizace Kukačka Z.Rosůlek M.Jelínek J.Slavata L.Kavan D.Novák P.Journal of Proteome Research. 2021; 20(4); 2021-202710.1021/acs.jproteome.0c00858
Studying Protein-DNA Interactions by Hydrogen/Deuterium Exchange Mass Spectrometry 2021 Laboratoř strukturní biologie a buněčné signalizace Filandrová R.Kavan D.Kádek A.Novák P.Man P.In: POTERSZMAN; Arnaud; ed. Multiprotein Complexes. Methods and Protocols. 2247. New York: Springer; 2021; s. 193-219. Methods in Molecular Biology10.1007/978-1-0716-1126-5_11
HSPA1A conformational mutants reveal a conserved structural unit in Hsp70 proteins 2020 Laboratoř strukturní biologie a buněčné signalizace Vandová V.Vaňková P.Durech M.Houser J.Kavan D.Man P.Muller P.Trčka F.Biochimica et Biophysica Acta-General Subjects. 2020; 1864(1); 12945810.1016/j.bbagen.2019.129458
The interaction of the mitochondrial protein importer TOMM34 with HSP70 is regulated by TOMM34 phosphorylation and binding to 14-3-3 adaptors 2020 Laboratoř regulace genové expreseTrčka F.Durech M.Vaňková P.Vandová V.Šimončík O.Kavan D.Vojtěšek B.Muller P.Man P.Journal of Biological Chemistry. 2020; 295(27); 8928-894410.1074/jbc.RA120.012624
Three-Dimensional Printed Target Plates for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry 2020 Laboratoř strukturní biologie a buněčné signalizace Fialová J.Hrabák J.Studentová V.Kavan D.Pompach P.Novák P.Analytical Chemistry. 2020; 92(19); 12783-1278810.1021/acs.analchem.0c01737
Structural Dynamics of Lytic Polysaccharide Monooxygenase during Catalysis 2020 Laboratoř strukturní biologie a buněčné signalizace Filandr F.Kavan D.Kracher D.Laurent C.Ludwig R.Man P.Halada P.Biomolecules. 2020; 10(2); 24210.3390/biom10020242
Production of recombinant soluble dimeric C-type lectin-like receptors of rat natural killer cells 2019 Laboratoř strukturní biologie a buněčné signalizace Vaněk O.Celadová P.Skořepa O.Bláha J.Kalousková B.Dvorská A.Poalchová E.Pucholtová H.Kavan D.Pompach P.Hofbauerová K.Kopecký V.Mesci A.Voigt S.Carlyle J.Scientific Reports. 2019; 9(NOV28); 1783610.1038/s41598-019-52114-8
MS-Based Approaches Enable the Structural Characterization of Transcription Factor/DNA Response Element Complex 2019 Laboratoř charakterizace molekulární strukturySlavata L.Chmelík J.Kavan D.Filandrová R.Fiala J.Rosůlek M.Mrázek H.Kukačka Z.Vališ K.Man P.Miller M.McIntyre W.Fabris D.Novák P.Biomolecules. 2019; 9(10); 53510.3390/biom9100535
Binding of eIF3 in complex with eIF5 and eIF1 to the 40S ribosomal subunit is accompanied by dramatic structural changes 2019 Laboratoř strukturní biologie a buněčné signalizace Zeman J.Itoh Y.Kukačka Z.Rosůlek M.Kavan D.Kouba T.Jansen M.Mohammad M.Novák P.Valášek L.Nucleic Acids Research. 2019; 47(15); 8282-830010.1093/nar/gkz570
Reductant-Induced Free Radical Fluoroalkylation of Nitrogen Heterocycles and Innate Aromatic Amino Acid Residues in Peptides and Proteins 2019 Laboratoř strukturní biologie a buněčné signalizace Rahimidashaghoul K.Klimánková I.Hubálek M.Korecký M.Chvojka M.Pokorný D.Matoušek V.Fojtík L.Kavan D.Kukačka Z.Novák P.Beier P.Chemistry - A European Journal. 2019; 25(69); 15779-1578510.1002/chem.201902944
Thiopurine intolerance-causing mutations in NUDT15 induce temperature-dependent destabilization of the catalytic site 2019 Laboratoř strukturní biologie a buněčné signalizace Man P.Fábry M.Sieglová I.Kavan D.Novák P.Hnízda A.Biochimica Et Biophysica Acta-Proteins and Proteomics. 2019; 1867(4); 376-38110.1016/j.bbapap.2019.01.006
