Nature Communications. 2024; 15(1); 2528
RNDr. Marek Kovář, Ph.D.
Head of Laboratory
Publication
Nanomedicine: Nanotechnology; Biology and Medicine. 2024; 56(February 2024); 102730
Chemosensitization of tumors via simultaneous delivery of STAT3 inhibitor and doxorubicin through HPMA copolymer-based nanotherapeutics with pH-sensitive activation.
Trends in Immunology. 2023; 44(11); 890-901
IL-2-driven CD8+ T cell phenotypes: implications for immunotherapy
Cell Death & Disease. 2023; 14(3); 209
Type I interferon signaling in malignant blasts contributes to treatment efficacy in AML patients
eLife. 2023; 12(Jan 27); e79342
Regulatory T cells suppress the formation of potent KLRK1 and IL- 7R expressing effector CD8 T cells by limiting IL-2
Journal of Controlled Release. 2023; 353(January); 549-562
Evaluation of linear versus star-like polymer anti-cancer nanomedicines in mouse models
Frontiers in Immunology. 2022; 13(OCT 10 2022); 989895
SOT101 induces NK cell cytotoxicity and potentiates antibody-dependent cell cytotoxicity and anti-tumor activity
Nanomedicine: Nanotechnology; Biology and Medicine. 2022; 44(August); 102578
Metastatic spread inhibition of cancer cells through stimuli-sensitive HPMA copolymer-bound actinonin nanomedicines
Pharmaceutics. 2022; 14(6); 1201
HPMA copolymer mebendazole conjugate allows systemic administration and possesses antitumour activity in vivo
eLife. 2021; 10(DEC 21 2021); e62432
IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-gamma production by CD25(+)Foxp3(-) T cells
eLife. 2021; 10(MAY 18 2021); e65777
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist
Oncoimmunology. 2021; 10(1); 1889822
TIM-3 levels correlate with enhanced NK cell cytotoxicity and improved clinical outcome in AML patients
Journal of Controlled Release. 2021; 332(APR 10 2021); 563-580
Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling
Haematologica-The Hematology Journal. 2020; 105(7); 1868-1878
Calreticulin exposure on malignant blasts correlates with improved natural killer cell-mediated cytotoxicity in acute myeloid leukemia patients
Cytokine. 2020; 133(SEP 2020); 155174
IL-7/alpha IL-7 mAb M25 immunocomplexes expand CD8(+) T cells but paradoxically abrogate the antitumor activity of CTLA-4 and PD-1 blockage
Elife . 2021 Dec 21;10:e62432