BIOCEV – Biotechnology and Biomedicine Centre of the Academy of Science and Charles University
Research & development represents one of the three basic pillars of project BIOCEV. Research & development performed in BIOCEV is focused on the selected areas of biotechnologies and biomedicine. The scientific scope of BIOCEV has been divided into five research programmes, each of them dealing with a number of separate research projects. The programmes and projects have been designed to form a mutually integrated system of synergistic links inside BIOCEV.
Focus of research
Functional Genomics
The genomes of humans, mice and many other species have been completely sequenced; nevertheless the knowledge of genome sequences as such does not shed light on questions concerning the functions of these sequences.
Cellular Biology and Virology
This programme includes four synergic and mutually complementing sub-programmes: Eukaryotic Microbiology, Biology of Cancer Cells, Virology and Structure and Differentiation of Mammalian Cells.
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Structural Biology and Protein Engineering
This program is focused on research of novel biotechnologically, diagnostically, and medically important biomolecules, proteins and nucleic acids that are constructed using state-of-the-art methods of molecular biology and protein engineering.
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Biomaterials and Tissue Engineering
The programme is focused on advanced trends in medicine aimed at usage of sophisticated tissue prostheses systems composed of synthetic materials combined with specific biologically active compounds and cells for regeneration and replacement of diseased tissues and organs or for controlled drug and gene delivery targeted to specific tissues and cells in diseased organism.
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Development of Diagnostic and Therapeutic Procedures
This programme includes a spectrum of projects covering reproductive medicine, diabetic complications, autoimmune and selected tumour diseases, inherited metabolic disorders, and study of heme pathology…
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Implementation of complex projects requires a high-quality methodological basis concentrated in the core facilities. All are open to external users to provide them with research services. Research infrastructures within the BIOCEV are: CCP – Czech Centre for Phenogenomics, CIISB – Czech Infrastructure for Integrative Structural Biology, Czech-BioImaging – National research infrastructure for biological and medical imaging and ELIXIR-CZ – national hub for bioinformatics and National Center for Medical Genomics.
