RNDr. Milada Šírová, Ph.D.

Vědecký pracovník

Publication

Block copolymer for overcoming drug resistance of tumours to chemotherapy; its polymer-drug conjugate; pharmaceutical composition containing them; method of preparation and use thereof

Evaluation of linear versus star-like polymer anti-cancer nanomedicines in mouse models

SOT101 induces NK cell cytotoxicity and potentiates antibody-dependent cell cytotoxicity and anti-tumor activity

Metastatic spread inhibition of cancer cells through stimuli-sensitive HPMA copolymer-bound actinonin nanomedicines

Simultaneous delivery of doxorubicin and protease inhibitor derivative to solid tumors via star-shaped polymer nanomedicines overcomes P-gp- and STAT3-mediated chemoresistance

Glycopolymers Decorated with 3-O-Substituted Thiodigalactosides as Potent Multivalent Inhibitors of Galectin-3

Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling

HPMA-based copolymers carrying STAT3 inhibitor cucurbitacin-D as stimulus-sensitive nanomedicines for oncotherapy

Blokový kopolymer pro překonání lékové rezistence nádorů k chemoterapii; jeho polymerní konjugát s léčivem; farmaceutická kompozice je obsahující; způsob jejich přípravy a jejich použití

Polymer nanomedicines based on micelle-forming amphiphilic or water-soluble polymer-doxorubicin conjugates: comparative study of in vitro and in vivo properties related to the polymer carrier structure; composition; and hydrodynamic properties

HPMA-based star polymer biomaterials with tuneable structure and biodegradability tailored for advanced drug delivery to solid tumours

Micelle-forming block copolymers tailored for inhibition of P-gp-mediated multidrug resistance: structure to activity relationship

HPMA polymer conjugates with cucurbitacin-D and doxorubicin intended for immuno-oncotherapy

Novel water-soluble biodegradable star-like polymer therapeutics

Micellar nanotherapeutics for treatment of solid tumours: a comparative study

Micellar nanoterapeutics for treatment of solid tumours: a comparative study

Micellar HPMA polymer-drug conjugates for immunooncotherapy

Biodegradable polymer carriers for therapy and diagnostic of solid tumor