ChemCatChem. 2024; 16(11); e202400028
doc. RNDr. Pavla Bojarová, Ph.D.
Head of Laboratory
Publication
Journal of Agricultural and Food Chemistry. 2024; 72(28); 15613-15623
Three-Step Enzymatic Remodeling of Chitin into Bioactive Chitooligomers
Process Biochemistry. 2024; 142(July 2024); 62-67
Biotransformation of free cyanide to formic acid by a cyanide hydratase-formamidase cascade reaction
Journal of Medicinal Chemistry. 2024; 67(11); 9214-9226
Glycopolymer Inhibitors of Galectin-3 Suppress the Markers of Tissue Remodeling in Pulmonary Hypertension
Bioorganic Chemistry. 2024; 148(July 2024); 107452
Diaminocyclopentane – l-Lysine Adducts: Potent and selective inhibitors of human O-GlcNAcase
Bioorganic Chemistry. 2024; 147(June 2024); 107395
Synthesis and unexpected binding of monofluorinated N;N?-diacetylchitobiose and LacdiNAc to wheat germ agglutinin.
Bioorganic Chemistry. 2024; 145(April 24); 107231
Glycomimetic inhibitors of tandem-repeat galectins: Simple and efficient
Journal of Agricultural and Food Chemistry. 2024; 72(40); 22208-22216
New Bacterial Aryl Sulfotransferases: Effective Tools for Sulfation of Polyphenols
In: Book of abstracts. Bratislava: Institute of Chemistry; Slovak Academy of Science; 2024; s. 45; č. článku OP10
FLUORINE-INDUCED STRENGTHENING OF C?H/? INTERACTION AS AN IMPORTANT DRIVING FORCE BEHIND THE RECOGNITION OF FLUORINATED DISACHARIDES BY WHEAT GERM AGGLUTININE
Bioorganic Chemistry. 2023; 140(November 2023); 106819
Highly functionalized diaminocyclopentanes: A new route to potent and selective inhibitors of human O-GlcNAcase
Chemical Communications. 2023; 59(69); 10404-10407
Galectin-targeting glycocalix[4]arenes can enter the cells
Biotechnology Advances. 2023; 68(Nov 2023); 108217
Rutinosidase and other diglycosidases: Rising stars in biotechnology
Molecules. 2023; 28(10); 4039
Oligosaccharide Ligands of Galectin-4 and Its Subunits: Multivalency Scores Highly
Critical Reviews in Environmental Science and Technology. 2023; 53(3); 416-434
Recent trends in the treatment of cyanide-containing effluents: Comparison of different approaches
Molecules. 2023; 28(4); 1728
Hesperidin; Hesperetin; Rutinose; and Rhamnose Act as Skin Anti-Aging Agents
Organic & Biomolecular Chemistry. 2023; 21(6); 1294-1302
Glycocalix[4]arenes and their affinity to a library of galectins: the linker matters
Bioorganic Chemistry. 2023; 131(February); 106279
Advanced high-affinity glycoconjugate ligands of galectins
In: Book of Abstracts. 2022
Structural Properties of Deoxyfluorinated Analogues of N-acetyllactosamine; N; N’-diacetyllactosamine and; N; N’-diacetylchitobiose
International Journal of Molecular Sciences. 2022; 23(20); 12456
Mutation Hotspot for Changing the Substrate Specificity of beta-N-Acetylhexosaminidase: A Library of GlcNAcases
ChemSusChem. 2022; 15(18); e202201253
Bacterial Aryl Sulfotransferases in Selective and Sustainable Sulfation of Biologically Active Compounds using Novel Sulfate Donors
Chemical Communications. 2022; 58(63); 8838-8841
Diaminocyclopentane-derived O-GlcNAcase inhibitors for combating tau hyperphosphorylation in Alzheimer’s disease
Biotechnology Advances. 2022; 58(SEP 2022); 107928
Methods of in vitro study of galectin-glycomaterial interaction
Bioorganic Chemistry. 2022; 120(March 2022); 105650
Discovery of human hexosaminidase inhibitors by in situ screening of a library of mono- and divalent pyrrolidine iminosugars
Advanced Synthesis & Catalysis. 2022; 364(12); 2009-2022
Hypertransglycosylating Variants of the GH20 beta-N-Acetylhexosaminidase for the Synthesis of Chitooligomers
International Journal of Molecular Sciences. 2022; 23(8); 4106
Engineered Glycosidases for the Synthesis of Analogs of Human Milk Oligosaccharides
Journal of Medicinal Chemistry. 2022; 65(5); 3866-3878
Glycopolymers Decorated with 3-O-Substituted Thiodigalactosides as Potent Multivalent Inhibitors of Galectin-3
International Journal of Molecular Sciences. 2022; 23(3); 1037
2-Acetamido-2-deoxy-d-glucono-1;5-lactone Sulfonylhydrazones: Synthesis and Evaluation as Inhibitors of Human OGA and HexB Enzymes
International Journal of Molecular Sciences. 2021; 22(13); 6661
Reversible Lectin Binding to Glycan-Functionalized Graphene
In: ŘÁPKOVÁ; R.; FUSEK; M.; DRAŠAR; P.; eds. Czech Chemial Society Symposium Series; Vol 19; No 1. Praha: Česká společnost chemická; 2021; s. 22-23
Deoxyfluorination as a Promising Synthetic Approach to Selective Carbohydrate-based Galectin Inhibitors.
ChemCatChem. 2021; 13(21); 4532-4542
Mutagenesis of Catalytic Nucleophile of beta-Galactosidase Retains Residual Hydrolytic Activity and Affords a Transgalactosidase
Biotechnology Advances. 2021; 49(JUL-AUG); 107733
Advanced glycosidases as ingenious biosynthetic instruments
In: New Approaches to State Security Assurance. Brno: Universita obrany v Brně; 2021; s. 223-227
Enzymatic detoxification of cyanide using cyanide hydratases
Chemistry - A European Journal. 2021; 27(51); 13040-13051
Selectively Deoxyfluorinated N-Acetyllactosamine Analogues as 19F NMR Probes to Study Carbohydrate-Galectin Interactions.
European Journal of Medicinal Chemistry. 2021; 220(AUG 5 2021); 113500
Immunoprotective neo-glycoproteins: Chemoenzymatic synthesis of multivalent glycomimetics for inhibition of cancer-related galectin-3
International Journal of Molecular Sciences. 2021; 22(10); 5144
Interaction between Galectin-3 and Integrins Mediates Cell-Matrix Adhesion in Endothelial Cells and Mesenchymal Stem Cells
International Journal of Molecular Sciences. 2021; 22(11); 6000
Cross-linking effects dictate the preference of galectins to bind LacNAc-decorated HPMA copolymers
International Journal of Molecular Sciences. 2021; 22(4); 1843
Growth Factors VEGF-A(165) and FGF-2 as Multifunctional Biomolecules Governing Cell Adhesion and Proliferation
Catalysis Communication. 2021; 149(JAN 15); 106193
Access to both anomers of rutinosyl azide using wild-type rutinosidase and its catalytic nucleophile mutant
International Journal of Biological Macromolecules. 2020; 161(OCT15); 1206-1215
Transglycosidase activity of glycosynthase-type mutants of a fungal GH20 beta-N-acetylhexosaminidase
Advanced Synthesis & Catalysis. 2020; 362(19); 4138-4150
How Site-Directed Mutagenesis Boosted Selectivity of a Promiscuous Enzyme
International Journal of Molecular Sciences. 2020; 21(16); 5671
Dual Substrate Specificity of the Rutinosidase fromAspergillus nigerand the Role of Its Substrate Tunnel
Chemistry - A European Journal. 2020; 26(43); 9620-9631
Regioselective 3-O-Substitution of Unprotected Thiodigalactosides: Direct Route to Galectin Inhibitors
International Journal of Molecular Sciences. 2020; 21(14); 5115
Biocatalysis: ´A Jack of all Trades …´
Biomacromolecules. 2020; 21(8); 3122-3133
Glycopolymers for efficient inhibition of galectin-3: in vitro proof of efficacy using suppression of T lymphocyte apoptosis and tumor cell migration
Biochimica Et Biophysica Acta-Proteins and Proteomics. 2020; 1868(2); 140319
A novel enzymatic tool for transferring GalNAc moiety onto challenging acceptors
International Journal of Molecular Sciences. 2019; 20(24); 6181
Acceptor Specificity of ?-N-Acetylhexosaminidase from Talaromyces flavus: A Rational Explanation
Applied Microbiology and Biotechnology. 2019; 103(19); 7869-7881
beta-N-Acetylhexosaminidases-the wizards of glycosylation
Advanced Synthesis & Catalysis. 2019; 361(11); 2627-2637
Glycosidase-Catalyzed Synthesis of Glycosyl Esters and Phenolic Glycosides of Aromatic Acids
In: Abstract Book. Heraklion: European Polymer Federation; 2019; s. 771
HPMA copolymers decorated with saccharide ligands: the architecture of spacer matters
Applied Microbiology and Biotechnology. 2019; 103(4); 1737-1753
Selective Beta-N-acetylhexosaminidase from Aspergillus versicolor—a tool for producing bioactive carbohydrates
International Journal of Molecular Sciences. 2019; 20(5); 1112
Bioproduction of Quercetin and Rutinose Catalyzed by Rutinosidase: Novel Concept of´Solid State Biocatalysis´
Molecules. 2019; 24(3); 599
The beta-N-Acetylhexosaminidase in the Synthesis of Bioactive Glycans: Protein and Reaction Engineering
Trends in Biotechnology. 2019; 37(4); 402-415