Ing. Natalia Kulik, Ph.D.

Vědecký asistent

Publication

Three-Step Enzymatic Remodeling of Chitin into Bioactive Chitooligomers

Biotransformation of free cyanide to formic acid by a cyanide hydratase-formamidase cascade reaction

Diaminocyclopentane – l-Lysine Adducts: Potent and selective inhibitors of human O-GlcNAcase

Glycomimetic inhibitors of tandem-repeat galectins: Simple and efficient

Immobilization of aldoxime dehydratases on metal affinity resins and use of the immobilized catalysts for the synthesis of nitriles important in fragrance industry

Dimerisation of the Yeast K+Translocation Protein Trk1 Depends on the K+Concentration

Flavonoids as Aglycones in Retaining Glycosidase-Catalyzed Reactions: Prospects for Green Chemistry

Computational Study of Complex Formation between Hyaluronan Polymers and Polyarginine Peptides at Various Ratios

Highly functionalized diaminocyclopentanes: A new route to potent and selective inhibitors of human O-GlcNAcase

Recent Progress in the Production of Cyanide-Converting Nitrilases-Comparison with Nitrile-Hydrolyzing Enzymes

Scanning aldoxime dehydratase sequence space and characterization of a new aldoxime dehydratase from Fusarium vanettenii

Modulation of global stability; ligand binding and catalytic properties of trypsin by anions

Mutation Hotspot for Changing the Substrate Specificity of beta-N-Acetylhexosaminidase: A Library of GlcNAcases

Diaminocyclopentane-derived O-GlcNAcase inhibitors for combating tau hyperphosphorylation in Alzheimer’s disease

Discovery of human hexosaminidase inhibitors by in situ screening of a library of mono- and divalent pyrrolidine iminosugars

Hypertransglycosylating Variants of the GH20 beta-N-Acetylhexosaminidase for the Synthesis of Chitooligomers

Interactions between a dsDNA Oligonucleotide and Imidazolium Chloride Ionic Liquids: Effect of Alkyl Chain Length; Part I

Mutagenesis of Catalytic Nucleophile of beta-Galactosidase Retains Residual Hydrolytic Activity and Affords a Transgalactosidase

MPM motifs of the yeast SKT protein Trk1 can assemble to form a functional K+-translocation system

Biocatalyzed Reactions towards Functional Food Components 4-Alkylcatechols and Their Analogues

Transglycosidase activity of glycosynthase-type mutants of a fungal GH20 beta-N-acetylhexosaminidase

How Site-Directed Mutagenesis Boosted Selectivity of a Promiscuous Enzyme

Plant Nitrilase Homologues in Fungi: Phylogenetic and Functional Analysis with Focus on Nitrilases in Trametes versicolor and Agaricus bisporus

The study of conformational changes in photosystem II during a charge separation

Acceptor Specificity of ?-N-Acetylhexosaminidase from Talaromyces flavus: A Rational Explanation

Genetic and Functional Diversity of Nitrilases in Agaricomycotina

Selective Beta-N-acetylhexosaminidase from Aspergillus versicolor—a tool for producing bioactive carbohydrates

The beta-N-Acetylhexosaminidase in the Synthesis of Bioactive Glycans: Protein and Reaction Engineering