Three-Step Enzymatic Remodeling of Chitin into Bioactive Chitooligomers 2024 Laboratoř biotransformacíMészáros Z.Kulik N.Petrásková L.Bojarová P.Texido M.Planas A.Křen V.Slámová K.Journal of Agricultural and Food Chemistry. 2024; 72(28); 15613-1562310.1021/acs.jafc.4c03077
Biotransformation of free cyanide to formic acid by a cyanide hydratase-formamidase cascade reaction 2024 Laboratoř biotransformacíMartínková L.Kulik N.Rucká L.Kotík M.Křístková B.Šťastná K.Novotný P.Příhodová R.Bojarová P.Pátek M.Process Biochemistry. 2024; 142(July 2024); 62-6710.1016/j.procbio.2024.04.009
Diaminocyclopentane – l-Lysine Adducts: Potent and selective inhibitors of human O-GlcNAcase 2024 Laboratoř biotransformacíWeber P.Bojarová P.Brouzdová J.Křen V.Kulik N.Stütz A.Thonhofer M.Wrodnigg T.Bioorganic Chemistry. 2024; 148(July 2024); 10745210.1016/j.bioorg.2024.107452
Glycomimetic inhibitors of tandem-repeat galectins: Simple and efficient 2024 Laboratoř biotransformacíVrbata D.Červený J.Kulik N.Hovorková M.Balogová S.Vlachová M.Pelantová H.Křen V.Bojarová P.Bioorganic Chemistry. 2024; 145(April 24); 10723110.1016/j.bioorg.2024.107231
Immobilization of aldoxime dehydratases on metal affinity resins and use of the immobilized catalysts for the synthesis of nitriles important in fragrance industry 2024 Laboratoř biotransformacíKřístková B.Martínková L.Rucká L.Kotík M.Kulik N.Rädisch R.Winkler M.Pátek M.Journal of Biotechnology. 2024; 384(20 March 2024); 12-1910.1016/j.jbiotec.2024.02.005
Dimerisation of the Yeast K+Translocation Protein Trk1 Depends on the K+Concentration 2023 Kulik N.Kale D.Spurná K.Shamayeva K.Hauser F.Milic S.Janout H.Zayats V.Jacak J.Ludwig J.International Journal of Molecular Sciences. 2023; 24(1); 39810.3390/ijms24010398
Flavonoids as Aglycones in Retaining Glycosidase-Catalyzed Reactions: Prospects for Green Chemistry 2023 Laboratoř biotransformacíKotík M.Kulik N.Valentová K.Journal of Agricultural and Food Chemistry. 2023; 71(41); 14890-1491010.1021/acs.jafc.3c04389
Computational Study of Complex Formation between Hyaluronan Polymers and Polyarginine Peptides at Various Ratios 2023 Kulik N.Minofar B.Jugl A.Pekař M.Langmuir. 2023; 39(40); 14212-1422210.1021/acs.langmuir.3c01318
Highly functionalized diaminocyclopentanes: A new route to potent and selective inhibitors of human O-GlcNAcase 2023 Laboratoř biotransformacíWeber P.Mészáros Z.Bojarová P.Ebner M.Fischer R.Křen V.Kulik N.Müller P.Vlachová M.Slámová K.Stütz A.Thonhofer M.Torvisco A.Wrodnigg T.Wolfsgruber A.Bioorganic Chemistry. 2023; 140(November 2023); 10681910.1016/j.bioorg.2023.106819
Recent Progress in the Production of Cyanide-Converting Nitrilases-Comparison with Nitrile-Hydrolyzing Enzymes 2023 Laboratoř biotransformacíMartínková L.Kulik N.Sedova A.Křístková B.Bojarová P.Catalysts. 2023; 13(3); 50010.3390/catal13030500
Scanning aldoxime dehydratase sequence space and characterization of a new aldoxime dehydratase from Fusarium vanettenii 2023 Laboratoř biotransformacíKřístková B.Rädisch R.Kulik N.Horvat M.Rucká L.Grulich M.Rudroff F.Kádek A.Pátek M.Winkler M.Martínková L.Enzyme and Microbial Technology. 2023; 164(MAR 2023); 11018710.1016/j.enzmictec.2022.110187
Modulation of global stability; ligand binding and catalytic properties of trypsin by anions 2022 Dušeková E.Garajová K.Yavaşer R.Tomková M.Sedláková D.Dzurillová V.Kulik N.Fadaei F.Shaposhnikova A.Minofar B.Sedlák E.Biophysical Chemistry. 2022; 288(September 2022); 10685610.1016/j.bpc.2022.106856
Mutation Hotspot for Changing the Substrate Specificity of beta-N-Acetylhexosaminidase: A Library of GlcNAcases 2022 Laboratoř biotransformacíNekvasilová P.Kulik N.Kotík M.Petrásková L.Slámová K.Křen V.Bojarová P.International Journal of Molecular Sciences. 2022; 23(20); 1245610.3390/ijms232012456
Diaminocyclopentane-derived O-GlcNAcase inhibitors for combating tau hyperphosphorylation in Alzheimer’s disease 2022 Laboratoř biotransformacíWeber P.Mészáros Z.Jagecic D.Hribljan V.Mitrečic D.Bojarová P.Slámová K.Vrba J.Kulik N.Křen V.Stuetz A.Chemical Communications. 2022; 58(63); 8838-884110.1039/d2cc02712g
Discovery of human hexosaminidase inhibitors by in situ screening of a library of mono- and divalent pyrrolidine iminosugars 2022 Laboratoř biotransformacíPingitore V.Martinez-Bailen M.Carmona A.Mészáros Z.Kulik N.Slámová K.Křen V.Bojarová P.Robina I.Moreno-Vargas A.Bioorganic Chemistry. 2022; 120(March 2022); 10565010.1016/j.bioorg.2022.105650
Hypertransglycosylating Variants of the GH20 beta-N-Acetylhexosaminidase for the Synthesis of Chitooligomers 2022 Laboratoř biotransformacíMészáros Z.Petrásková L.Kulik N.Pelantová H.Bojarová P.Křen V.Slámová K.Advanced Synthesis & Catalysis. 2022; 364(12); 2009-202210.1002/adsc.202200046
Interactions between a dsDNA Oligonucleotide and Imidazolium Chloride Ionic Liquids: Effect of Alkyl Chain Length; Part I 2022 Fadaei F.Seifert M.Raymond J.Řeha D.Kulik N.Minofar B.Heitz M.Molecules. 2022; 27(1); 11610.3390/molecules27010116
Mutagenesis of Catalytic Nucleophile of beta-Galactosidase Retains Residual Hydrolytic Activity and Affords a Transgalactosidase 2021 Laboratoř biotransformacíHovorková M.Kulik N.Konvalinková D.Petrásková L.Křen V.Bojarová P.ChemCatChem. 2021; 13(21); 4532-454210.1002/cctc.202101107
MPM motifs of the yeast SKT protein Trk1 can assemble to form a functional K+-translocation system 2021 Shamayeva K.Spurná K.Kulik N.Kale D.Munko O.Spurný P.Zayats V.Ludwig J.Biochimica Et Biophysica Acta-Biomembranes. 2021; 1863(2); 18351310.1016/j.bbamem.2020.183513
Biocatalyzed Reactions towards Functional Food Components 4-Alkylcatechols and Their Analogues 2020 Laboratoř biotransformacíMartínková L.Příhodová R.Kulik N.Pelantová H.Křístková B.Petrásková L.Biedermann D.Catalysts. 2020; 10(9); 107710.3390/catal10091077
Transglycosidase activity of glycosynthase-type mutants of a fungal GH20 beta-N-acetylhexosaminidase 2020 Laboratoř biotransformacíKapešová J.Petrásková L.Kulik N.Straková Z.Bojarová P.Markošová K.Rebroš M.Křen V.Slámová K.International Journal of Biological Macromolecules. 2020; 161(OCT15); 1206-121510.1016/j.ijbiomac.2020.05.273
How Site-Directed Mutagenesis Boosted Selectivity of a Promiscuous Enzyme 2020 Laboratoř biotransformacíNekvasilová P.Kulik N.Rychlá N.Pelantová H.Petrásková L.Bosáková Z.Cvačka J.Slámová K.Křen V.Bojarová P.Advanced Synthesis & Catalysis. 2020; 362(19); 4138-415010.1002/adsc.202000604
Plant Nitrilase Homologues in Fungi: Phylogenetic and Functional Analysis with Focus on Nitrilases in Trametes versicolor and Agaricus bisporus 2020 Biotechnologická hala Rucká L.Kulik N.Novotný P.Sedova A.Petrásková L.Příhodová R.Křístková B.Halada P.Pátek M.Martínková L.Molecules. 2020; 25(17); 386110.3390/molecules25173861
The study of conformational changes in photosystem II during a charge separation 2020 Kulik N.Kutý M.Řeha D.Journal of Molecular Modeling. 2020; 26(4); 7510.1007/s00894-020-4332-9
Acceptor Specificity of ?-N-Acetylhexosaminidase from Talaromyces flavus: A Rational Explanation 2019 Laboratoř biotransformacíGarcia-Oliva C.Hoyos P.Petrásková L.Kulik N.Pelantová H.Cabanillas A.Rumbero A.Křen V.Hernáiz M.Bojarová P.International Journal of Molecular Sciences. 2019; 20(24); 618110.3390/ijms20246181
Genetic and Functional Diversity of Nitrilases in Agaricomycotina 2019 Biotechnologická hala Rucká L.Chmátal M.Kulik N.Petrásková L.Pelantová H.Novotný P.Příhodová R.Pátek M.Martínková L.International Journal of Molecular Sciences. 2019; 20(23); 599010.3390/ijms20235990
Selective Beta-N-acetylhexosaminidase from Aspergillus versicolor—a tool for producing bioactive carbohydrates 2019 Laboratoř biotransformacíBojarová P.Kulik N.Slámová K.Hubálek M.Kotík M.Cvačka J.Pelantová H.Křen V.Applied Microbiology and Biotechnology. 2019; 103(4); 1737-175310.1007/s00253-018-9534-z
The beta-N-Acetylhexosaminidase in the Synthesis of Bioactive Glycans: Protein and Reaction Engineering 2019 Laboratoř biotransformacíBojarová P.Kulik N.Hovorková M.Slámová K.Pelantová H.Křen V.Molecules. 2019; 24(3); 59910.3390/molecules24030599