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Microbial Lipids

Laboratory of Fungal Genetics and Metabolism
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Microbial Lipids

Lipids are essential components of all cells, serving as fundamental building blocks of cellular membranes and as energy sources. Our work focuses on the detailed characterization of lipid composition in bacteria, fungi, and algae. These microorganisms produce “single cell oils” with triacylglycerols (TAG) as the main component. TAGs are important sources of polyunsaturated fatty acids and other unusual fatty acids essential for human and animal nutrition, and they are also used as sources of third-generation biofuels. Our research impacts the ecology and biochemistry of organisms as well as applied microbiology, with a focus on human nutrition and biofuels.

The main results are summarized in the following works, highlighting the extent of our collaboration with various teams from the Czechia and abroad.

  • Timkina E, Kulišová M, Palyzová A, Marešová H, Maťátková O, Řezanka T, et al. (2024) Isolation and characterization of multiple-stress tolerant bacteria from radon springs. PLoS ONE 19(3): e0299532
  • Kyselová L, Řezanka T (2024) Analysis of glycosylated cardiolipins from thermophilic bacteria using GC–MS and LC–ESI–MS/MS methods, Journal of Pharmaceutical and Biomedical Analysis, 38: 115800
  • Kyselová L, Řezanka T (2024) Stereochemistry of aminoacylated cardiolipins and phosphatidylglycerols from bacteria. Electrophoresis. 45: 980–988.
  • Řezanka T, Hršelová H, Kyselová L. et al. (2023) Can cardiolipins be used as a biomarker for arbuscular mycorrhizal fungi?. Mycorrhiza 33: 399–408
  • Timkina E, Kolouchová I, Kyselová L, Palyzová A, Murphy D, Řezanka T (2023) Off-line two-dimensional LC–tandem MS of menaquinones from thermophilic bacteria. Food Chemistry. 431. 137112.
  • Řezanka T, Kyselová L, Murphy DJ (2023) Archaeal lipids, Progress in Lipid Research, Volume 91: 101237
  • Lukavský J, Kopecký J, Kubáč D. et al. (2023) The alga Bracteacoccus bullatus (Chlorophyceae) isolated from snow, as a source of oil comprising essential unsaturated fatty acids and carotenoids. J Appl Phycol 35: 649–660
  • Procházková L, Matsuzaki R, Řezanka, T., Nedbalová, L. and Remias, D. (2023), The snow alga Chloromonas kaweckae sp. nov. (Volvocales, Chlorophyta) causes green surface blooms in the high tatras (Slovakia) and tolerates high irradiance. J. Phycol., 59: 236-24