Farmaceutický přípravek pro léčbu lékově rezistentních bakteriálních infekcí 2023 Laboratoř biotransformacíViktorová J.Křen V.Holasová K.Macek T.Valentová K.Biedermann D.Dobiasová S.
Selectively Halogenated Flavonolignans—Preparation and Antibacterial Activity 2022 Laboratoř biotransformacíHurtová M.Káňová K.Dobiasová S.Holasová K.Čáková D.Hoang L.Biedermann D.Kuzma M.Cvačka J.Křen V.Viktorová J.Valentová K.International Journal of Molecular Sciences. 2022; 23(23); 1512110.3390/ijms232315121
Stability and ultraviolet A photostability of silymarin polyphenols and its consequences for practical use in dermatology 2022 Laboratoř biotransformacíKosina P.Ryšavá A.Vostálová J.Papoušková B.Biedermann D.Ulrichová J.Svobodová A.Journal of Photochemistry and Photobiology A-Chemistry. 2022; 429(1 August); 11389710.1016/j.jphotochem.2022.113897
Preparation of Synthetic and Natural Derivatives of Flavonoids Using Suzuki-Miyaura Cross-Coupling Reaction 2022 Laboratoř biotransformacíHurtová M.Biedermann D.Osifová Z.Cvačka J.Valentová K.Křen V.Molecules. 2022; 27(3); 96710.3390/molecules27030967
Silymarin dehydroflavonolignans chelate zinc and partially inhibit alcohol dehydrogenase 2021 Laboratoř biotransformacíTvrdý V.Hrubša M.Jirkovský E.Biedermann D.Kutý M.Valentová K.Křen V.Mladěnka P.Nutrients. 2021; 13(12); 423810.3390/nu13124238
Continuous diastereomeric kinetic resolution—silybins a and b 2021 Laboratoř biotransformacíBiedermann D.Hurtová M.Benada O.Valentová K.Biedermannová L.Křen V.Catalysts. 2021; 11(9); 110610.3390/catal11091106
Flavonolignans from silymarin do not intercalate into DNA: Rebuttal of data published in the paper J. Mol. Recognit. e2812 (2019) 2021 Laboratoř biotransformacíBiedermann D.Hurtová M.Biedermannová L.Valentová K.Křen V.Journal of Molecular Recognition. 2021; 34(7); 288810.1002/jmr.2888
Dehydroflavonolignans from Silymarin Potentiate Transition Metal Toxicity In Vitro but Are Protective for Isolated Erythrocytes Ex Vivo 2021 Laboratoř biotransformacíLomozová Z.Tvrdý V.Hrubša M.Catapano M.Macáková K.Biedermann D.Kučera R.Křen V.Mladěnka P.Valentová K.Antioxidants. 2021; 10(5); 67910.3390/antiox10050679
Influence of silymarin components on keratinocytes and 3D reconstructed epidermis 2021 Laboratoř biotransformacíFranková J.Juráňová J.Biedermann D.Ulrichová J.Toxicology in Vitro. 2021; 74(AUG 2021); 10516210.1016/j.tiv.2021.105162
Mild and Selective Method of Bromination of Flavonoids 2020 Laboratoř biotransformacíHurtová M.Biedermann D.Kuzma M.Křen V.Journal of Natural Products. 2020; 83(11); 3324-333110.1021/acs.jnatprod.0c00655
Biocatalyzed Reactions towards Functional Food Components 4-Alkylcatechols and Their Analogues 2020 Laboratoř biotransformacíMartínková L.Příhodová R.Kulik N.Pelantová H.Křístková B.Petrásková L.Biedermann D.Catalysts. 2020; 10(9); 107710.3390/catal10091077
Multidrug Resistance Modulation Activity of Silybin Derivatives and Their Anti-Inflammatory Potential 2020 Laboratoř biotransformacíDobiasová S.Řehořová K.Kučerová D.Biedermann D.Káňová K.Petrásková L.Koucká K.Václavíková R.Valentová K.Ruml T.Macek T.Křen V.Viktorová J.Antioxidants. 2020; 9(5); 45510.3390/antiox9050455
Co-administration of silymarin elevates the therapeutic effect of praziquantel through modulation of specific antibody profiles; Th1/Th2/Tregs cytokines and down-regulation of fibrogenesis in mice with Mesocestoides vogae (Cestoda) infection 2020 Laboratoř biotransformacíHrčková G.Kubašková Mačák T.Reiterová K.Biedermann D.Experimental Parasitology. 2020; 213(JUN); 10788810.1016/j.exppara.2020.107888
Simple and Rapid HPLC Separation and Quantification of Flavonoid; Flavonolignans; and 2;3-Dehydroflavonolignans in Silymarin 2020 Laboratoř biotransformacíPetrásková L.Káňová K.Biedermann D.Křen V.Valentová K.Foods. 2020; 9(2); 11610.3390/foods9020116
Defying Multidrug Resistance! Modulation of Related Transporters by Flavonoids and Flavonolignans 2020 Laboratoř biotransformacíChambers C.Viktorová J.Řehořová K.Biedermann D.Turková L.Macek T.Křen V.Valentová K.Journal of Agricultural and Food Chemistry. 2020; 68(7); 1763-177910.1021/acs.jafc.9b00694
The effect of silymarin flavonolignans and their sulfated conjugates on platelet aggregation and blood vessels ex vivo 2019 Laboratoř biotransformacíPourová J.Applová L.Macáková K.Vopršalová M.Migkos T.Bentanachs R.Biedermann D.Petrásková L.Tvrdý V.Hrubša M.Karlíčková J.Křen V.Valentová K.Mladěnka P.Nutrients. 2019; 11(10); 228610.3390/nu11102286
2;3-Dehydroderivatives of Silymarin Flavonolignans: Prospective Natural Compounds for the Prevention of Chronic Diseases 2019 Laboratoř biotransformacíValentová K.Biedermann D.Křen V.Proceedings. 2019; 11(1); 2110.3390/proceedings2019011021
Antioxidant; Anti-Inflammatory; and Multidrug Resistance Modulation Activity of Silychristin Derivatives 2019 Laboratoř biotransformacíViktorová J.Dobiášová S.Řehořová K.Biedermann D.Káňová K.Šeborová K.Václavíková R.Valentová K.Ruml T.Křen V.Macek T.Antioxidants. 2019; 8(8); 30310.3390/antiox8080303
A pilot study of the UVA-photoprotective potential of dehydrosilybin; isosilybin; silychristin; and silydianin on human dermal fibroblasts 2019 Laboratoř biotransformacíSvobodová A.Gabrielová E.Ulrichová J.Zálešák B.Biedermann D.Vostálová J.Archives of Dermatological Research. 2019; 311(6); 477-49010.1007/s00403-019-01928-7
Chemoenzymatic Synthesis and Radical Scavenging of Sulfated Hydroxytyrosol; Tyrosol; and Acetylated Derivatives 2019 Laboratoř biotransformacíBegines P.Biedermann D.Valentová K.Petrásková L.Pelantová H.Maya I.Fernandez-Bolanos J.Křen V.Journal of Agricultural and Food Chemistry. 2019; 67(26); 7281-728810.1021/acs.jafc.9b01065
Preparation of Retinoyl-Flavonolignan Hybrids and Their Antioxidant Properties 2019 Laboratoř biotransformacíChambers C.Biedermann D.Valentová K.Petrásková L.Viktorová J.Kuzma M.Křen V.Antioxidants. 2019; 8(7); 23610.3390/antiox8070236
Skin Protective Activity of Silymarin and its Flavonolignans 2019 Laboratoř biotransformacíVostálová J.Tinková E.Biedermann D.Kosina P.Ulrichová J.Svobodová Rajnochová A.Molecules. 2019; 24(6); 102210.3390/molecules24061022
Oxidation of flavonolignan silydianin to unexpected lactone-acid derivative 2019 Laboratoř biotransformacíBiedermann D.Moravcová V.Valentová K.Kuzma M.Petrásková L.Císařová I.Křen V.Phytochemistry Letters. 2019; 30(APR); 14-2010.1016/j.phytol.2019.01.006
Dermal Delivery of Selected Polyphenols from Silybum marianum. Theoretical and Experimental Study 2019 Laboratoř biotransformacíKosina P.Paloncýová M.Svobodová A.Zálešák B.Biedermann D.Ulrichová J.Vostálová J.Molecules. 2019; 24(1); 6110.3390/molecules24010061
Modulation of Skin Inflammatory Response by Active Components of Silymarin 2019 Laboratoř biotransformacíJuráňová J.Aury-Landas J.Boumediene K.Bauge C.Biedermann D.Ulrichová J.Franková J.Molecules. 2019; 24(1); 12310.3390/molecules24010123
Isolated Silymarin Flavonoids Increase Systemic and Hepatic Bilirubin Concentrations and Lower Lipoperoxidation in Mice 2019 Laboratoř biotransformacíŠuk J.Jašprová J.Biedermann D.Petrásková L.Valentová K.Křen V.Muchová L.Vítek L.Oxidative Medicine and Cellular Longevity. 2019; 2019(1); 602690210.1155/2019/6026902
