RNDr. Helena Pelantová, Ph.D.

Vědecký pracovník

Publication

Expanding Rutinosidase Versatility: Acylated Quercetin Glucopyranosides as Substrates

Glycomimetic inhibitors of tandem-repeat galectins: Simple and efficient

Galectin-targeting glycocalix[4]arenes can enter the cells

Metabolomic Study of Aging in fa/fa Rats: Multiplatform Urine and Serum Analysis

Protective Effect of Vegan Microbiota on Liver Steatosis Is Conveyed by Dietary Fiber: Implications for Fecal Microbiota Transfer Therapy

Glycocalix[4]arenes and their affinity to a library of galectins: the linker matters

Advanced high-affinity glycoconjugate ligands of galectins

Sulfation of Phenolic Acids: Chemoenzymatic vs. Chemical Synthesis

New Bacterial Aryl Sulfotransferases: Effective Tools for Sulfation of Polyphenols

Bacterial Aryl Sulfotransferases in Selective and Sustainable Sulfation of Biologically Active Compounds using Novel Sulfate Donors

Hypertransglycosylating Variants of the GH20 beta-N-Acetylhexosaminidase for the Synthesis of Chitooligomers

Sulfated Phenolic Substances: Preparation and Optimized HPLC Analysis

Engineered Glycosidases for the Synthesis of Analogs of Human Milk Oligosaccharides

NMR- and MS-Based Untargeted Metabolomic Study of Stool and Serum Samples from Patients with Anorexia Nervosa

Glycopolymers Decorated with 3-O-Substituted Thiodigalactosides as Potent Multivalent Inhibitors of Galectin-3

Exploration of GH94 Sequence Space for Enzyme Discovery Reveals a Novel Glucosylgalactose Phosphorylase Specificity

Two fungal flavonoid-specific glucosidases/rutinosidases for rutin hydrolysis and rutinoside synthesis under homogeneous and heterogeneous reaction conditions

Immunoprotective neo-glycoproteins: Chemoenzymatic synthesis of multivalent glycomimetics for inhibition of cancer-related galectin-3

The intestinal microbiota and metabolites in patients with anorexia nervosa

Access to both anomers of rutinosyl azide using wild-type rutinosidase and its catalytic nucleophile mutant

Diet Rich in Simple Sugars Promotes Pro-Inflammatory Response via Gut Microbiota Alteration and TLR4 Signaling

Lipid Profiling in Epicardial and Subcutaneous Adipose Tissue of Patients with Coronary Artery Disease

Sulfated Metabolites of Luteolin; Myricetin; and Ampelopsin: Chemoenzymatic Preparation and Biophysical Properties

Biocatalyzed Reactions towards Functional Food Components 4-Alkylcatechols and Their Analogues

How Site-Directed Mutagenesis Boosted Selectivity of a Promiscuous Enzyme

Dual Substrate Specificity of the Rutinosidase fromAspergillus nigerand the Role of Its Substrate Tunnel

Regioselective 3-O-Substitution of Unprotected Thiodigalactosides: Direct Route to Galectin Inhibitors

A novel enzymatic tool for transferring GalNAc moiety onto challenging acceptors

Acceptor Specificity of ?-N-Acetylhexosaminidase from Talaromyces flavus: A Rational Explanation

Genetic and Functional Diversity of Nitrilases in Agaricomycotina

Identifying Efficient Clostridium difficile Toxin A Binders with a Multivalent Neo-Glycoprotein Glycan Library

Minor lipids profiling in subcutaneous and epicardial fat tissue using LC/MS with an optimized preanalytical phase

Chemoenzymatic Synthesis and Radical Scavenging of Sulfated Hydroxytyrosol; Tyrosol; and Acetylated Derivatives

Glycosidase-Catalyzed Synthesis of Glycosyl Esters and Phenolic Glycosides of Aromatic Acids

Metabolomics Based on MS in Mice with Diet-Induced Obesity and Type 2 Diabetes Mellitus: the Effect of Vildagliptin; Metformin; and Their Combination

Metabolomic Study of Obesity and Its Treatment with Palmitoylated Prolactin-Releasing Peptide Analog in Spontaneously Hypertensive and Normotensive Rats

Selective Beta-N-acetylhexosaminidase from Aspergillus versicolor—a tool for producing bioactive carbohydrates

Enzyme-mediated transglycosylation of rutinose (6-O-alpha-l-rhamnosyl-d-glucose) to phenolic compounds by a diglycosidase from Acremonium sp. DSM 24697

The beta-N-Acetylhexosaminidase in the Synthesis of Bioactive Glycans: Protein and Reaction Engineering