Molecular Biology of Bacterial Pathogens
Šebo LAB
We study tricks and tools used by pathogenic bacteria to suppress our immune defense. In particular, we study among other the emerging pediatric pathogen Kingella kingeae and the major focus is on the whooping cough agent Bordetella pertussis that causes the respiratory illness called pertussis. This infectious disease can be fatal to smallest non-vaccinated infants and is currently on the rise in the most developed and wealthiest countries (where vaccine refusal is on the rise and less reactogenic but also less efficacious pertussis vaccines are used).
Our credo is “knowledge is useful”. Through highest quality basic research, we strive for gaining of deepest understanding of “HOW IT WORKS”. At the same time, we search for ways how to use the acquired knowledge for the benefit of the taxpayer that funds our scientific work.
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Focus of research
This infectious disease can be fatal to the smallest non-vaccinated infants and is currently on the rise in the most developed and wealthiest countries (where vaccine refusal is on the rise and less reactogenic but also less efficacious pertussis vaccines are used).
Read morePublic services and cooperation
- Production and purification of recombinant proteins and construction of mutant strains of Bordetella pertussis
- Infection experiments in a mouse model
Our team
Meet the members of our Molecular Biology of Bacterial Pathogens team
Šebo Lab
