Cell communication and signaling : CCS. 2024; 22(1); 261
Ing. Radim Osička, Ph.D.
Senior scientist
Publication
Biochimica Et Biophysica Acta-Biomembranes. 2024; 1866(5); 184311
Modification of the RTX domain cap by acyl chains of adapted length rules the formation of functional hemolysin pores.
Nature. 2023; 624(7992); 653-662
Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease.
Cell Reports. 2023; 42(10); 113240
Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis
Microbial Pathogenesis. 2023; 181(AUG); 106200
Kingella kingae RtxA toxin interacts with sialylated gangliosides
Journal of Biological Chemistry. 2023; 299(8); 104978
A conserved tryptophan in the acylated segment of RTX toxins controls their ?inf2/inf integrin–independent cell penetration
Scientific Reports. 2023; 13(1); 1471
Early evolution of enamel matrix proteins is reflected by pleiotropy of physiological functions
International Journal of Molecular Sciences. 2022; 23(20); 12598
Filamentous Hemagglutinin of Bordetella pertussis Does Not Interact with the ?2 Integrin CD11b/CD18
Microorganisms. 2022; 10(3); 518
Kingella kingae RtxA Cytotoxin in the Context of Other RTX Toxins
International Journal of Molecular Sciences. 2021; 22(21); 11655
Selective enhancement of the cell-permeabilizing activity of adenylate cyclase toxin does not increase virulence of bordetella pertussis
Scientific Reports. 2021; 11(1); 19814
Different roles of conserved tyrosine residues of the acylated domains in folding and activity of RTX toxins
International Journal of Molecular Sciences. 2021; 22(16); 9064
Bordetella Adenylate Cyclase Toxin Elicits Airway Mucin Secretion through Activation of the cAMP Response Element Binding Protein
Journal of Biological Chemistry. 2021; 297(1); 100833
Almost half of the RTX domain is dispensable for complement receptor 3 binding and cell-invasive activity of the Bordetella adenylate cyclase toxin
International Journal of Molecular Sciences. 2020; 21(23); 9092
Binding of Kingella kingae RtxA Toxin Depends on Cell Surface Oligosaccharides; but Not on beta(2) Integrins
Toxins. 2020; 12(9); 596
Production of Highly Active Recombinant Dermonecrotic Toxin ofBordetella Pertussis
Journal of Biological Chemistry. 2020; 295(28); 9268-9280
Acyltransferase-mediated selection of the length of the fatty acyl chain and of the acylation site governs activation of bacterial RTX toxins
Journal of Biological Chemistry. 2020; 295(28); 9349-9365
Retargeting from the CR3 to the LFA-1 receptor uncovers the adenylyl cyclase enzyme?translocating segment ofBordetellaadenylate cyclase toxin
Toxins. 2019; 11(6); 336
Rapid Purification of Endotoxin-Free RTX Toxins
Scientific Reports. 2019; 9(APR 8); 5758