Petr Man - Mikrobiologický ústav AV ČR, v. v. i.

Analytical Chemistry. 2024; 96(19); 7386-7393

Structural Characterization of Monoclonal Antibodies and Epitope Mapping by FFAP Footprinting

Communications Biology. 2024; 7(1); 463

Structural dynamics of Na+ and Ca2+ interactions with full-size mammalian NCX

FEBS Letters. 2024; 598(4); 485-499

Insights into the pathogenesis of primary hyperoxaluria type I from the structural dynamics of alanine:glyoxylate aminotransferase variants

In: GEVAERT; K.; ed. Mass Spectrometry-Based Proteomics. New York: Humana; 2023; s. 303-334. Methods in Molecular Biology

Probing Antibody Structures by Hydrogen/Deuterium Exchange Mass Spectrometry

In: WEINERT; E.E.; ed. Oxygen Sensing. Methods and Protocols. New York: Humana; 2023; s. 99-122

Hydrogen/Deuterium Exchange Mass Spectrometry of Heme-Based Oxygen Sensor Proteins

Journal of Biological Chemistry. 2023; 299(8); 104978

A conserved tryptophan in the acylated segment of RTX toxins controls their ?inf2/inf integrin–independent cell penetration

FEBS Journal. 2023; 290(7); 1855-1873

Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease-associated NQO1 enzyme

FEBS Letters. 2022; 596(1); 29-41

A single evolutionarily divergent mutation determines the different FAD-binding affinities of human and rat NQO1 due to site-specific phosphorylation

Antioxidants. 2022; 11(6); 1110

Allosteric Communication in the Multifunctional and Redox NQO1 Protein Studied by Cavity-Making Mutations

Archives of Biochemistry and Biophysics. 2022; 729(OCT 30 2022); 109392

Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations

Scientific Reports. 2022; 12(1); 17200

Loss of stability and unfolding cooperativity in hPGK1 upon gradual structural perturbation of its N-terminal domain hydrophobic core

Communications Biology. 2022; 5(1); 886

TTYH family members form tetrameric complexes at the cell membrane

Science Advances. 2022; 8(20); eabn1171

Structural basis for long-chain isoprenoid synthesis by cis-prenyltransferases

DeutEx

International Journal of Biological Macromolecules. 2021; 174(MAR 31 2021); 413-423

Early modification of cytochrome c by hydrogen peroxide triggers its fast degradation

Redox Biology. 2021; 46(OCT 2021); 102112

Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue

Enzyme and Microbial Technology. 2021; 148(AUG 2021); 109801

Functional expression and characterization of two laccases from the brown rot Fomitopsis pinicola

ACS Catalysis. 2021; 11(2); 517-532

Chimeric Cellobiose Dehydrogenases Reveal the Function of Cytochrome Domain Mobility for the Electron Transfer to Lytic Polysaccharide Monooxygenase

In: POTERSZMAN; Arnaud; ed. Multiprotein Complexes. Methods and Protocols. 2247. New York: Springer; 2021; s. 193-219. Methods in Molecular Biology

Studying Protein-DNA Interactions by Hydrogen/Deuterium Exchange Mass Spectrometry

Journal of the American Chemical Society. 2020; 142(7); 3440-3448

Different Reaction Specificities of F420H2-Dependent Reductases Facilitate Pyrrolobenzodiazepines and Lincomycin To Fit Their Biological Targets

Biochimica et Biophysica Acta-General Subjects. 2020; 1864(1); 129458

HSPA1A conformational mutants reveal a conserved structural unit in Hsp70 proteins

Journal of Biological Chemistry. 2020; 295(27); 8928-8944

The interaction of the mitochondrial protein importer TOMM34 with HSP70 is regulated by TOMM34 phosphorylation and binding to 14-3-3 adaptors

FEBS Letters. 2020; 594(7); 1196-1206

Bacteriocin ASM1 is an O/S-diglycosylated; plasmid-encoded homologue of glycocin F

Scientific Reports. 2020; 10(1); 4119

Photoinduced damage of AsLOV2 domain is accompanied by increased singlet oxygen production due to flavin dissociation

Biotechnology for Biofuels. 2020; 13(1); 37

The H2O2-dependent activity of a fungal lytic polysaccharide monooxygenase investigated with a turbidimetric assay

Nature Communications. 2020; 11(1); 5273

Structural basis of heterotetrameric assembly and disease mutations in the human cis-prenyltransferase complex

FASEB Journal. 2020; 34(8); 9925-9940

Conserved cysteine dioxidation enhances membrane interaction of human Cl(-)intracellular channel 5

Biomolecules. 2020; 10(2); 242

Structural Dynamics of Lytic Polysaccharide Monooxygenase during Catalysis

FEBS Journal. 2020; 287(16); 3494-3510

14-3-3 protein binding blocks the dimerization interface of caspase-2

Biomolecules. 2019; 9(11); 728

A Dynamic Core in Human NQO1 Controls the Functional and Stability Effects of Ligand Binding and Their Communication across the Enzyme Dimer

Biomolecules. 2019; 9(10); 535

MS-Based Approaches Enable the Structural Characterization of Transcription Factor/DNA Response Element Complex

Nature Methods. 2019; 16(7); 595-602

Recommendations for performing; interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

Analytical Chemistry. 2019; 91(17); 10970-10978

Improving the Sequence Coverage of Integral Membrane Proteins during Hydrogen/Deuterium Exchange Mass Spectrometry Experiments

Journal of Proteomics. 2019; 204(JUL 30); 103411

A three-pronged ‘Pitchfork’ strategy enables an extensive description of the human membrane proteome and the identification of missing proteins

Toxins. 2019; 11(8); 439

Ergochromes: Heretofore Neglected Side of Ergot Toxicity

Biochimica Et Biophysica Acta-Proteins and Proteomics. 2019; 1867(4); 376-381

Thiopurine intolerance-causing mutations in NUDT15 induce temperature-dependent destabilization of the catalytic site

Molecular & Cellular Proteomics. 2019; 18(2); 320-337

RNDr. Petr Man, Ph.D.

Publication

Structural Characterization of Monoclonal Antibodies and Epitope Mapping by FFAP Footprinting

Structural dynamics of Na+ and Ca2+ interactions with full-size mammalian NCX

Insights into the pathogenesis of primary hyperoxaluria type I from the structural dynamics of alanine:glyoxylate aminotransferase variants

Probing Antibody Structures by Hydrogen/Deuterium Exchange Mass Spectrometry

Hydrogen/Deuterium Exchange Mass Spectrometry of Heme-Based Oxygen Sensor Proteins

A conserved tryptophan in the acylated segment of RTX toxins controls their ?inf2/inf integrin–independent cell penetration

Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease-associated NQO1 enzyme

A single evolutionarily divergent mutation determines the different FAD-binding affinities of human and rat NQO1 due to site-specific phosphorylation

Allosteric Communication in the Multifunctional and Redox NQO1 Protein Studied by Cavity-Making Mutations

Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations

Loss of stability and unfolding cooperativity in hPGK1 upon gradual structural perturbation of its N-terminal domain hydrophobic core

TTYH family members form tetrameric complexes at the cell membrane

Structural basis for long-chain isoprenoid synthesis by cis-prenyltransferases

DeutEx

Early modification of cytochrome c by hydrogen peroxide triggers its fast degradation

Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue

Functional expression and characterization of two laccases from the brown rot Fomitopsis pinicola

Chimeric Cellobiose Dehydrogenases Reveal the Function of Cytochrome Domain Mobility for the Electron Transfer to Lytic Polysaccharide Monooxygenase

Studying Protein-DNA Interactions by Hydrogen/Deuterium Exchange Mass Spectrometry

Different Reaction Specificities of F420H2-Dependent Reductases Facilitate Pyrrolobenzodiazepines and Lincomycin To Fit Their Biological Targets

HSPA1A conformational mutants reveal a conserved structural unit in Hsp70 proteins

The interaction of the mitochondrial protein importer TOMM34 with HSP70 is regulated by TOMM34 phosphorylation and binding to 14-3-3 adaptors

Bacteriocin ASM1 is an O/S-diglycosylated; plasmid-encoded homologue of glycocin F

Photoinduced damage of AsLOV2 domain is accompanied by increased singlet oxygen production due to flavin dissociation

The H2O2-dependent activity of a fungal lytic polysaccharide monooxygenase investigated with a turbidimetric assay

Structural basis of heterotetrameric assembly and disease mutations in the human cis-prenyltransferase complex

Conserved cysteine dioxidation enhances membrane interaction of human Cl(-)intracellular channel 5

Structural Dynamics of Lytic Polysaccharide Monooxygenase during Catalysis

14-3-3 protein binding blocks the dimerization interface of caspase-2

A Dynamic Core in Human NQO1 Controls the Functional and Stability Effects of Ligand Binding and Their Communication across the Enzyme Dimer

MS-Based Approaches Enable the Structural Characterization of Transcription Factor/DNA Response Element Complex

Recommendations for performing; interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

Improving the Sequence Coverage of Integral Membrane Proteins during Hydrogen/Deuterium Exchange Mass Spectrometry Experiments

A three-pronged ‘Pitchfork’ strategy enables an extensive description of the human membrane proteome and the identification of missing proteins

Ergochromes: Heretofore Neglected Side of Ergot Toxicity

Thiopurine intolerance-causing mutations in NUDT15 induce temperature-dependent destabilization of the catalytic site

Human Stress-inducible Hsp70 Has a High Propensity to Form ATP-dependent Antiparallel Dimers That Are Differentially Regulated by Cochaperone Binding

Search

Publication

Structural Characterization of Monoclonal Antibodies and Epitope Mapping by FFAP Footprinting

Structural dynamics of Na+ and Ca2+ interactions with full-size mammalian NCX

Insights into the pathogenesis of primary hyperoxaluria type I from the structural dynamics of alanine:glyoxylate aminotransferase variants

Probing Antibody Structures by Hydrogen/Deuterium Exchange Mass Spectrometry

Hydrogen/Deuterium Exchange Mass Spectrometry of Heme-Based Oxygen Sensor Proteins

A conserved tryptophan in the acylated segment of RTX toxins controls their ?inf2/inf integrin–independent cell penetration

Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease-associated NQO1 enzyme

A single evolutionarily divergent mutation determines the different FAD-binding affinities of human and rat NQO1 due to site-specific phosphorylation

Allosteric Communication in the Multifunctional and Redox NQO1 Protein Studied by Cavity-Making Mutations

Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations

Loss of stability and unfolding cooperativity in hPGK1 upon gradual structural perturbation of its N-terminal domain hydrophobic core

TTYH family members form tetrameric complexes at the cell membrane

Structural basis for long-chain isoprenoid synthesis by cis-prenyltransferases

DeutEx

Early modification of cytochrome c by hydrogen peroxide triggers its fast degradation

Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue

Functional expression and characterization of two laccases from the brown rot Fomitopsis pinicola

Chimeric Cellobiose Dehydrogenases Reveal the Function of Cytochrome Domain Mobility for the Electron Transfer to Lytic Polysaccharide Monooxygenase

Studying Protein-DNA Interactions by Hydrogen/Deuterium Exchange Mass Spectrometry

Different Reaction Specificities of F420H2-Dependent Reductases Facilitate Pyrrolobenzodiazepines and Lincomycin To Fit Their Biological Targets

HSPA1A conformational mutants reveal a conserved structural unit in Hsp70 proteins

The interaction of the mitochondrial protein importer TOMM34 with HSP70 is regulated by TOMM34 phosphorylation and binding to 14-3-3 adaptors

Bacteriocin ASM1 is an O/S-diglycosylated; plasmid-encoded homologue of glycocin F

Photoinduced damage of AsLOV2 domain is accompanied by increased singlet oxygen production due to flavin dissociation

The H2O2-dependent activity of a fungal lytic polysaccharide monooxygenase investigated with a turbidimetric assay

Structural basis of heterotetrameric assembly and disease mutations in the human cis-prenyltransferase complex

Conserved cysteine dioxidation enhances membrane interaction of human Cl(-)intracellular channel 5

Structural Dynamics of Lytic Polysaccharide Monooxygenase during Catalysis

14-3-3 protein binding blocks the dimerization interface of caspase-2

A Dynamic Core in Human NQO1 Controls the Functional and Stability Effects of Ligand Binding and Their Communication across the Enzyme Dimer

MS-Based Approaches Enable the Structural Characterization of Transcription Factor/DNA Response Element Complex

Recommendations for performing; interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

Improving the Sequence Coverage of Integral Membrane Proteins during Hydrogen/Deuterium Exchange Mass Spectrometry Experiments

A three-pronged ‘Pitchfork’ strategy enables an extensive description of the human membrane proteome and the identification of missing proteins

Ergochromes: Heretofore Neglected Side of Ergot Toxicity

Thiopurine intolerance-causing mutations in NUDT15 induce temperature-dependent destabilization of the catalytic site

Human Stress-inducible Hsp70 Has a High Propensity to Form ATP-dependent Antiparallel Dimers That Are Differentially Regulated by Cochaperone Binding